March 10 –
Beauty tip of the month


I have marionette lines on my face. I’m thinking about getting a filler to deal with them. How do I know which filler to ask for?

There are so many cosmetic fillers on the market today and the field develops so rapidly that it can get a bit confusing. So let us review some of the newer additions to the family.

As you know, the history of cosmetic fillers began with bovine (cow) collagen more than twenty years ago. Bovine collagen is rarely used these days because it is short-lived (a few weeks) and there is a very high potential for allergic reactions.

Recently the FDA approved a bioengineered human collagen that consists of collagen originally derived from human cells. While this bioengineered human collagen does not pose the same allergy risk as traditional bovine collagen, the results are still very short-lived (two to three months) compared to other fillers.

Another soft-tissue filler that received FDA approval recently is a nonanimal-derived hyaluronic acid under the trade name of Restyline or Peryline. Hyaluronic acid is a naturally occurring component of the skin. Compared to collagen, hyaluronic acid works better in improving nasolabial folds and marionette lines. The results last longer (four to six months), there is no allergy risk, and there is no risk of transmitting animalborne diseases. It has been used in Canada, Europe, and Australia with great success and is regarded by many doctors as perhaps one of the most superior fillers that currently exists.

For patients who want longer-lasting results, there is a new filler known by the trade name Radiance. This new scientific filler contains beads of hydroxyapatite, a substance normally used to replace missing bone.

For patients looking for permanent wrinkle fillers, one of the new injectables currently awaiting FDA approval in the United States is polymethylmethacrylate. This is made from a mixture of micronized plastic spheres and bovine collagen. Polymethylmethacrylate has been shown to work well for moderate to deep wrinkles and scars, but it is not recommended for lips. The results of polymethylmethacrylate are permanent, so it is extremely important that you go to a dermatologist or surgeon who is experience in the procedure.

My suggestion is to start with a nonpermanent hyaluronic acid-based injection and see how you like the effect. Afterward you can move on to a more permanent filler.


Dr. Adrienne Denese, M.D.
Secrets For Ageless Skin

You may also like this:

2 Comments on "March 10 –
Beauty tip of the month"

  1. Esther says:

    The latest FDA approved filler is Juvederm, a hyaluronic acid filler which gives the most natural-looking results & lasts up to 12 months. It even comes with pre-filled lidocaine (an anaesthetic), so the process is almost painless!
    I’ve tried it & love it! especially, no pain.

  2. Violet says:

    Hi Shirleen!

    I hope you don’t mind me directing this question to Esther. So how is the plumping effect with Juvederm? Obvious? Any bumps to contend with? How’s the bruising?

Got something to say? Go for it!

two × = 10